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Description

20% of NB patients and drives half of the aggressive forms of the disease with poor outcomes ( MYCN transcriptional machinery, synthetic lethality, and destabilization of the MYCN protein ( NB, like other malignancies, is associated with modifications in cellular metabolism that may contribute to oncogenesis

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In addition, the db/db + Reta group demonstrated superior efficacy in reducing alanine aminotransferase, aspartate aminotransferase, total cholesterol, triglyceride, and low-density lipoprotein levels

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Linus Pauling Institute Oregon State University Updated in March 2017 by: Barbara Delage, Ph.D

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